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Bridging Guidelines and Real-World Practice in IgA Nephropathy

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The KDIGO 2025 guidelines for IgA nephropathy broaden diagnostic and treatment strategies by promoting earlier kidney biopsy consideration and setting stricter proteinuria targets while advocating a dual-focused therapeutic approach that simultaneously limits pathogenic IgA immune complex formation and addresses nephron loss with both traditional supportive care and newer agents such as targeted-release budesonide, sparsentan, and SGLT2 inhibitors.

Exploring the Complex Nature of IgA Nephropathy

EP. 1: Exploring the Complex Nature of IgA Nephropathy

Anitha Vijayan, MD;Kartik Kalra, MD
December 22nd 2025

Explore the complexities of IgA nephropathy, its treatment advancements, and the challenges in early diagnosis and management in nephrology.

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The Impact of Underdiagnosis and a Pivotal Moment in Care

EP. 2: The Impact of Underdiagnosis and a Pivotal Moment in Care

Anitha Vijayan, MD;Kartik Kalra, MD
December 22nd 2025

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Evolving Management and Pathogenesis of IgA Nephropathy

EP. 3: Evolving Management and Pathogenesis of IgA Nephropathy

Anitha Vijayan, MD;Kartik Kalra, MD
January 8th 2026

Explore the evolution of IgA nephropathy treatment, highlighting new guidelines and targeted therapies that improve patient outcomes.

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Diagnosis and Risk Stratification in IgA Nephropathy: Biopsy and Biomarkers

EP. 4: Diagnosis and Risk Stratification in IgA Nephropathy: Biopsy and Biomarkers

Anitha Vijayan, MD;Kartik Kalra, MD
January 8th 2026

Explore the evolution of IgA nephropathy treatment, highlighting new guidelines and targeted therapies that improve patient outcomes.

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Historical and Evolving Approaches to IgA Nephropathy: From Supportive Care to Updated Guidelines

EP. 5: Historical and Evolving Approaches to IgA Nephropathy: From Supportive Care to Updated Guidelines

Anitha Vijayan, MD;Kartik Kalra, MD
January 15th 2026

Explore the evolving treatments for IgA nephropathy, highlighting the shift towards proactive strategies and the role of Nefecon in patient care.

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Evidence-Based Therapies Targeting the Heterogeneity of IgA Nephropathy

EP. 6: Evidence-Based Therapies Targeting the Heterogeneity of IgA Nephropathy

Anitha Vijayan, MD;Kartik Kalra, MD
January 15th 2026

Explore the evolving treatments for IgA nephropathy, highlighting the shift towards proactive strategies and the role of Nefecon in patient care.

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2 experts are featured in this series.

EP. 7: Aligning Treatment Goals in IgA Nephropathy: Applying KDIGO’s Dual-Pathway Framework to Clinical Decision-Making

Gerald Appel, MD ;Luis Sanchez Russo, MD
February 6th 2026

Explore KDIGO 2025 IgA nephropathy shifts: treat earlier at proteinuria >0.5 g/day, dual-pathway therapy aims to preserve GFR.

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