AAAAI: American Academy of Allergy, Asthma and Immunology

To optimize use of biologics for asthma, greater attention should be paid to adherence, according to an abstract prepared and published for the American Academy of Allergy, Asthma & Immunology 2020 Annual Meeting.

Two studies discussed the feasibility of different parameters for the infusion of a product for patients with primary immunodeficiency disorder in abstracts prepared for the American Academy of Allergy, Asthma & Immunology 2020 Annual Meeting.

The study noted that few oral immunotherapy (OIT) studies include patients with a history of severe reactions requiring epinephrine.

Is it cost-effective to prescribe epinephrine to every patient on allergen immunotherapy (AIT)? Does AIT have an impact on healthcare costs? These and other issues were included among the research prepared and published for the American Academy of Allergy, Asthma & Immunology 2020 Annual Meeting.

High infusion parameters for pump-assisted and manual push 20% subcutaneous immunoglobulin (SCIg), or IgPro20, were well tolerated by patients with primary immunodeficiency disorder (PID), according to a recent abstract prepared for the American Academy of Allergy, Asthma & Immunology 2020 Annual Meeting.

Included among the abstracts prepared and published for the American Academy of Allergy, Asthma & Immunology 2020 Annual Meeting are several that looked at the clinical and psychosocial factors that complicate asthma in pediatric patients. A few are highlighted here.

The first US patients with peanut allergy have been treated with Aimmune Therapeutic’s Palforzia oral immunotherapy (OIT), the company said. The treatment was approved by the FDA in January, and is the first approved treatment for patients with peanut allergy.

The American Journal of Managed Care® discussed the prevalence of poor indoor air quality in childcare facilities with Joshua Steinberg, MD, assistant professor of pediatrics at the Medical College of Wisconsin, and Erin Lee, a clinical research coordinator at the Medical College of Wisconsin.

The American Journal of Managed Care® (AJMC®) dicussed the efficacy of ragweed sublingual immunotherapy (SLIT) tablets with Anne Ellis, MD, professor of medicine and chair of the Division of Allergy & Immunology at Queen's University in Kingston, Ontario, Canada.

The American Journal of Managed Care® (AJMC®) interviewed Elisabet Johansson, PhD, a research fellow at the University of Cincinnati, about how the gene NFE2L2 interacts with secondhand smoke, and increases the risk of asthma.

Researchers tested berberine containing natural medicine (BCNM) in mice with peanut allergy and found the treatment regimen induced long-term tolerance to peanut and a profound, sustained reduction of immunoglobulin E (IgE). In an interview with The American Journal of Managed Care®, Kamal Srivastava, PhD, director of Basic Science Research at General Nutraceutical Technology, explained the growing importance of gut and skin microbiota when it comes to treatment of food allergy.

The American Journal of Managed Care® discussed the real-world burden of reduced quality of life among adolescents with peanut allergies with Anna Nowak-Węgrzyn, MD, PhD, professor of pediatrics at the New York University School of Medicine, Department of Pediatrics, Langone Health, New York.

Despite a patient's vigilance, there is an unpredictable risk of an accidental reaction from an exposure, explained Brian Vickery, MD, associate professor of pediatrics at Emory University and director of the Food Allergy Center, Children’s Healthcare of Atlanta.

Researchers are encouraged by a set of peanut allergy immunotherapy data released Sunday at the 2019 American Academy of Allergy, Asthma & Immunology Annual Meeting, but they said that more discoveries are needed to understand which treatment might be best suited for patients.

There are greater awareness efforts taking place to educate other specialists on referring patients who are having suspected allergic reactions to the appropriate allergists, who can do a fuller evaluation, said Scott P. Commins, MD, PhD, associate professor of medicine, at the University of North Carolina.

Some children treated with egg oral immunotherapy (OIT) are likely to continue eating and tolerating egg 5 years after treatment, according to research that may someday lead to the development of biomarkers to predict who will respond to OIT. The research was presented at the 2019 Annual Meeting of the American Academy of Allergy, Asthma & Immunology.

Two abstracts presented Saturday at The American Academy of Allergy, Asthma & Immunology 2019 Annual Meeting, held February 22-25 in San Francisco, California, discussed how formulary switching can affect outcomes for patients with severe persistent asthma, as well as how improving outcomes may be associated with increased quality measures.

Three studies presented Saturday at the American Academy of Allergy, Asthma and Immunology 2019 Annual Meeting, held February 22-25 in San Francisco, California, discussed different topics related to hereditary angioedema and treatment with subcutaneous injection of C1-esterase inhibitor (C1-INH).

Two abstracts presented Saturday at the American Academy of Allergy, Asthma & Immunology 2019 Annual Meeting, held February 22-25 in San Francisco, California, covered various links among economics, asthma control, and medication use.

Data about who is affected by sesame allergy, the ninth allergen in the United States, were released in an effort to convince the FDA to label it as a major food allergen.

Even when there are treatment failures, the knowledge gained through food allergy studies helps to move the field forward, explained Robert A. Wood, MD, director, Pediatric Allergy and Immunology, Johns Hopkins Medicine; 2018-2019 president, American Academy of Allergy, Asthma, and Immunology (AAAAI).

Did you think biology only involved studying people, animals, and plants? How about tumors, or maybe cells? Keep going. Smaller. A lot smaller.

A sunrise session on climate change, followed by Tuesday's poster session on allergen immunotherapy at the 2014 Annual Meeting of the American Academy of Allergy, Asthma & Immunology (AAAAI) in San Diego, California, highlighted the irony: Thanks in no small part to the cost of navigating the approval process of the US Food and Drug Administration (FDA), Europe has more options to treat seasonal allergies, even though America has far more ragweed.

The American Academy of Allergy, Asthma & Immunology (AAAAI) on Monday released its second list of overused tests and procedures that allergists, primary care physicians, and patients should question before they occur. The list represents the fruits of the Academy's second year of participation in the Choosing Wisely initiative, and was presented at a press conference during the Academy's meeting in San Diego, California.

Taking care of asthma patients costs the nation $56 billion a year, and included in that total are the costs of the many sufferers who do not properly follow their prescriptions.

Researchers seeking to reduce the dangers of peanut allergies have seen encouraging results in recent years from oral immunotherapy. But many questions remain: How large of a dose? For how long? And, once treatment ends, does its effectiveness last, or does it eventually wear off?

Two oral immunotherapy treatments for allergic rhinitis being developed by Merck and ALK-Abello, which received separate approvals in recent months from the Allergenic Products Advisory Panel (APAC) of the US Food and Drug Administration (FDA),1,2 are the subject of results presented Monday at the 2014 Annual Meeting of the American Academy of Allergy, Asthma & Immunology in San Diego, California.

Some of the same themes being raised across medicine-how to balance the quality of care with soaring therapy costs, and how to unleash the power of genomics to tailor treatment-were part of Saturday's workshop Hot Topics in Pediatric Allergy and Immunology. The session of the American Academy of Pediatrics took place during the 2014 Annual Meeting of the American Academy of Allergy, Asthma & Immunology in San Diego, California.

Asthma is among the diseases for which adherence presents challenges, both to physicians and to manufacturers of therapies. Two studies presented Saturday at the 2014 Annual Meeting of the American Academy of Allergy, Asthma & Immunology in San Diego, California, discuss an attempt by one manufacturer, Merck, to overcome the problem through the development of an adherence estimator called AE.

The introduction for Eric J. Topol, MD, who gave the keynote address Saturday at the 2014 Annual Meeting of the American Academy of Allergy, Asthma & Immunology (AAAAI) in San Diego, California, ended with the usual instruction: Please silence your cell phone.