:root {
    --primary: #5c514e;
    --secondary: rgb(130, 140, 0);
    --text: #006460;
  }
  .ipub-wrapper * {
    font-family: 'Montserrat';
  }
  .top-ad-container {
    position: relative;
    z-index: 99;
  }
  .ipub-wrapper p {
    margin-bottom: 0;
  }
  .video-container {
    box-sizing: border-box;
    display: flex;
    flex-direction: column;
    justify-content: space-between;
  }
  .ipub-inner-wrapper {
    width: 1291px;
    max-width: 90vw;
    background: 0 0;
    padding: 1.25rem 0.25rem 2rem;
    margin-top: 6rem;
  }
  .ipub-navbar-container {
    display: flex;
    justify-content: flex-start;
    width: 1291px;
    max-width: 90vw;
    margin: 0 2rem;
  }
  .ipub-navbar {
    background: #FFFFFF;
    border-bottom: 5px solid #b2d2ea;
    padding: 0.5rem 0;
  
  }
  .chapter,
  .chapter-tab {
      color: #fff;
      text-align: center;
      font-size: 1.5rem;
      font-weight: 500;
      margin-right: 0;
      padding-left: 1rem;
      padding-right: 1rem;
      transition: all 0.2s;
      display: flex;
      justify-content: center;
      align-items: center;
  }
  
  .chapter {
      color: white;
      min-width: 3.5%;
      flex: 1 1 auto;
      background: #989999;
      font-family: 'Montserrat';
  }
  .chapter:hover {
    text-decoration: none;
    color: #2b294d !important;
    background: #a8c5de;
  }
  .chapter:not(:last-child) {
    border-right: 1px solid #eee;
  }
  .chapter:nth-child(2) {
    border-left: 1px solid #eee;
  }
  .chapter:not(.active):hover span:last-child {
    opacity: 1;
    color: #2b294d;
    width: 100%;
  }
  .ipub-wrapper {
    position: relative;
    width: 100vw;
    height: 100%;
    background: transparent linear-gradient(180deg, #3E8DDD 0%, #1865B2 47%, #FFFFFF 100%) 0% 0% no-repeat padding-box;;
    background-size: 120%;
    background-repeat: no-repeat;
    background-position: top;
    min-height: 130vh;
    display: flex;
    align-items: center;
    flex-direction: column;
    background-color: #E8E8E8;
  }
  .ipub-chapters {
    display: flex;
    justify-content: center;
    flex-direction: row;
    flex-wrap: nowrap;
    width: 100%;
    min-height: 54px;
    position: relative;
    z-index: 2;
  }
  .ipub-prescription-info {
    display: flex;
    height: 55px;
    /* background: #969b1e; */
    position: relative;
    overflow: hidden;
  }
  .logo-container {
    display: flex;
    align-items: center;
  
  }
  .isi-container {
    width: 100%;
    height: 100%;
  }
  .ISIInnerBox h3 {
    color: #006998;
    font-weight: bold;
    margin-bottom: 0;
    font-size: 17px;
  }
  .ipub-top-indication {
    width: 700px;
    max-width: 80vw;
    height: 120px;
    margin: 0 auto;
    margin-top: 3rem;
    text-align: center;
    padding: 0 1.5rem;
    margin-bottom: 1rem;
  }
  .ipub-top-indication p:first-child {
    color: #f10086;
    font-weight: 700;
    margin-bottom: 0.5rem;
  }
  .ipub-player {
    background: #fff;
  
    position: relative;
    z-index: 2;
  
    box-shadow: 2px 4px 8px rgba(0, 0, 0, 0.5);
  }
  .ipub-prescription-info p {
    color: #fff;
  }
  .video-wrap .video-desc{
    height: '60px'; 
    background-color: '#0B2748';
    position: 'relative';
     display: 'flex';
     align-items:'center';
  }
  .video-desc h3{
    font-family: Arial;
    font-size: 24px;
    color: #FFFFFF;
  }
  .ipub-header {
    background: white;
    display: flex;
    flex-direction: row;
    flex-wrap: nowrap;
    justify-content: space-between;
    align-items: center;
    margin: 1rem auto ;
    overflow: hidden;
    color: #006998;
  }
  .ipub-header h3{
    padding-top: 2px;
    font-family: 'Montserrat';
    font-weight:500;
    color: #2B294D;
    font-size: 28px;
  }
  .isi-sub-title {
    margin-bottom: 0.25rem !important;
    font-size: 1.1rem;
    font-weight: 700;
    font-family: 'Montserrat';
  }
  .isi-sub-title-lg {
    margin-bottom: 0.25rem !important;
    font-size: 16px !important;
    font-weight: bold;
    font-family:'Montserrat';
  }
  .top-content{
    padding: 2rem 0;
  }
  .top-content h3{
    color: #006998;
    font-size: 16px;
    font-weight: 600;
  }
  .ipub-title h1 {
    color: #2B294D;
    font-size: 28px;
    font-weight: 700;
    padding: 1rem 0rem 1rem 0;
    line-height: 1.1;
    text-align: left;
    font-family: 'Montserrat';
  
  }
  .ipub-logo img {
    max-height: 55px;
  }
  .onc-logo img {
    max-height: 95px;
    margin-left: 2rem;
    margin-right: 5rem;
  }
  .ipub-video {
    border-top: 35px solid #0B2748;
    padding: 0 4.25rem;
    margin: 0 auto;
    max-width: 90vw;
    overflow: hidden;
  }
  .ipub-prescription-info {
    display: flex;
    height: 55px;
    position: relative;
    overflow: hidden;
  }
  .chapter:nth-child(2) {
    border-left: none;
  }
  .ipub-prescription-info a {
    text-decoration: underline;
    font-size: 0.9rem;
    color: #757575;
    padding: 0.1rem;
    cursor: pointer;
  }
  .ipub-prescription-info .current-title {
    z-index: 1;
    font-size: 20px;
    font-weight: bold;
    font-weight: 700;
    line-height: 1.2;
  }
  .chapter-title {
    line-height: 1;
  }
  .ipub-prescription-info p {
    position: absolute;
    left: 0;
    top: 0;
    width: 100%;
    margin: 0;
    height: 100%;
    display: flex;
    align-items: center;
    background: #0B2748;
    padding-left: 1rem;
    padding-right: .5rem;
    font-size: 1.2rem;
    line-height: 1.2;
    letter-spacing: 1px;
  }
  .ipub-chapters {
    display: flex;
    justify-content: center;
    flex-direction: row;
    flex-wrap: nowrap;
    width: 100%;
    min-height: 54px;
    position: relative;
    z-index: 2;
  }
  .chapter-tab {
    width: 20%;
    background-color:#0B2748;
    color: #fff !important;
  }
  .chapter,
  .chapter-tab {
    color: #fff;
    /* height: 40px;
    width: 100%; */
    text-align: center;
    font-size: 1.5rem;
    font-weight: 700;
    margin-right: 0;
    padding-left: 1rem;
    padding-right: 1rem;
    transition: all 0.2s;
    display: flex;
    justify-content: center;
    align-items: center;
  }
  /* .sub-chapters {
    display: flex;
  } */
  .chapter {
    color:#0B2748;
    min-width: 3.5%;
    flex: 1 1 auto;
    background: #D8E8F8;
  }
  .chapter span:last-child {
    position: absolute;
    top: calc(100% + 1px);
    left: 0;
    height: 100%;
    width: 99%;
    z-index: 1;
    opacity: 0;
    font-size: 24px;
    font-weight: bold;
    background: #0B2748;
    color: white;
    display: flex;
    align-items: center;
    padding-left: 1rem;
    text-align: left;
    font-weight: 600;
    letter-spacing: 1px;
    pointer-events: none;
  }
  .chapter:hover {
    text-decoration: none;
    color: #fff;
    background: #8ABAEA;
    line-height: 1;
  }
  .chapter:not(.active):hover span:last-child {
    opacity: 1;
    color: #fff;
  }
  .ipub-bottom {
    margin-top: 1rem;
    width: 100%;
  }
  .ipub-speaker,
  .program-objectives {
    background-color: #F0F5F8;
    max-width: 1146px;
    margin: 0 auto;
    position: relative;
    z-index: 2;
    max-width: 95vw;
    padding-top: 0.75rem;
  }
  .ipub-speaker p{
    color:'#5D6771';
    font-size:'9px';
    padding:'1rem';
  }
  .bg-switch{
    background-color: #F6F6F6;
  }
  .program-objectives {
    /* border-bottom: 1px solid #00000029; */
  }
  
  .speaker-individual-container {
    flex-direction: row !important;
    padding-bottom: 2rem;
    margin: 0 1.5rem;
    width: calc(50% - 3rem);
  }
  
  .ipub-speaker > h2,
  .program-objectives > h2 {
    width: 100%;
    font-size: 33px;
    font-family: 'Montserrat';
    text-transform: uppercase;
    color:#3E8DDD;
    font-weight: 600;
    text-align: center;
    margin-top: .5rem;
    margin-bottom: .5rem;
  }
  .centralize{
    text-align: center;
  }
  
  .speaker-container {
    display: flex;
    flex-direction: row;
    flex-wrap: wrap;
    padding: 1rem 0 0;
    padding-bottom: 1rem;
    /* border-bottom: 1px solid #00000029; */
  }
  
  .speaker-individual-container div {
    line-height: 1.4;
    height: 100%;
    width: 100%;
    padding-left: 1rem;
    /* padding-top: 20px; */
  }
  .speaker-individual-container div p{
    text-align: left;
    line-height: 1.2;
    color: #5D5D5F;
    font-size: 15px;
    font-family: 'Montserrat';
    font-weight: regular;
  }
  .speaker-individual-container div p:first-child {
    font-family: 'Montserrat';
    font-weight: 600;
    font-size: 12px;
    color: #2B294D;
  }
  .speaker-individual-container div p:nth-child(2){
    padding-top: 5px;
    font-family: 'Montserrat';
    font-weight: 700;
    font-size: 15px;
    color: #3E8DDD;
  }
  .speaker-container p {
    color: #000;
    text-align: left;
    font-size: 1.4rem;
  }
  .speaker-container img {
    height: 150px;
    width: 150px;
    border-radius: 50%;
    object-fit: cover;
    object-position: top;
    min-width: 150px;
  }
  .speaker-img {
    min-width: 220px;
    height: 220px;
    border-radius: 50%;
    overflow: hidden;
  }
  .speaker-img img {
    width: 220px;
    height: auto;
  }
  .cred {
    padding-left: 3rem;
    color: #006460;
  }
  .cred p {
    color: #006460;
    line-height: 1.6;
    margin-block-start: 0.25rem;
    margin-block-end: 0.25rem;
  }
  .active {
    background: #8ABAEA;
    color: #0B2748;
    font-size: 1.75rem;
    z-index: 1;
  }
  .intro.active {
    font-size: 1rem;
  }
  .active span {
    font-size: 1.5rem;
    line-height: 1;
    display: block;
  }
  .active span:first-child {
    font-size: 1.5rem;
  }
  .speaker-name {
    font-size: 1.8rem;
    font-weight: 700;
    color: #006460;
  }
  .speaker-loc {
    font-size: 1.2rem;
    margin-bottom: 0.75rem !important;
    color: #006460;
  }
  .ISIBox {
    border-radius: 0;
    background: #fff;
    display: flex;
    flex-direction: column;
    justify-content: space-between;
  }
  .ISI-header {
    background-color: #F07F33;
    color: #fff;
    font-weight: 600;
    font-size: 0.8rem;
    padding: 0.75rem;
  }
  .ISI-header a {
    color: #fff;
    text-decoration: underline;
  }
  .ISI-header p:first-child {
    font-size: 1.1rem;
    font-weight: 700;
  }
  .ISI-header p:last-child {
    font-weight: 300;
  }
  .ISIInnerBox {
    font: 400 12px/14px;
    line-height: 1.4;
    overflow-y: scroll;
    background: #fff;
    height: 250px;
    padding-top: 1rem;
    padding-left: 0.5rem;
    padding-right: 0.5rem;
    color: #000;
  }
  
  .ISIInnerBox p {
    font-size: 17px;
    margin-bottom: 1rem;
  }
  .ISIInnerBox h4 {
    color: #250858;
    font-size: 17px;
    font-weight: 700;
    margin-bottom: 0;
  }
  .isi-prescribing-info {
    background: #FFD8BE;
    color: #4c4c4c;
    padding: 0.75rem 1rem;
    font-size: 17px;
    font-weight: 700;
    text-align: center;
  
  }
  
  .isi-prescribing-info a {
    color: #066998;
    text-decoration: underline;
  }
  .ISIInnerBox::-webkit-scrollbar {
    width: 10px;
  }
  .ISIInnerBox::-webkit-scrollbar-track {
    background: #fff;
  }
  .ISIInnerBox::-webkit-scrollbar-thumb {
    background: #aaa;
    border-radius: 10px;
  }
  .ISIInnerBox ul li{
    margin-bottom: 1rem;
    padding: 2px;
    font-size: 17px;
  }
  .ISIInnerBox ul{
    padding: 1rem;
    margin: 0;
  }
  .mlr {
    margin: 0 auto;
    display: flex;
    flex-direction: row;
    flex-wrap: nowrap;
    max-width: 95vw;
    padding-top: 2rem;
    padding-bottom: 2rem;
  }
  .mlr div {
    font-size: 14px;
    text-align: left;
    color: #5D6771;
    margin-right: 1.7rem;
  }
  /* .mlr div:nth-of-type(even){
    margin-top: 1rem;
  } */
  
  .intro {
    width: 70px;
    font-size: 0.8rem;
  }
  
  /* program objectives */
  .objectives {
    display: flex;
    justify-content: flex-start;
    align-items: center;
    margin: 0 1rem;
    flex-wrap: wrap;
  }
  .obj-card {
    margin: 1rem;
    border:5px solid #0B2748;
    max-width: calc(50% - 2rem);
    flex: 1 1 auto;
    background: #FFFFFF;
    padding-left:0.5rem;
    display: flex;
    flex-direction: row;
    align-items: center;
    min-height: 150px;
  }
  .obj-body {
    width: 546px;
    height: 182.23px; 
  }
  .obj-body p {
    color: #444444;
    font-size: 18px;
  }
  .obj-img {
    width: 105px;
    min-width: 105px;
    min-height: 85px;
    display: flex;
    margin-right: 1rem;
    align-items: center;
  }
  .bottom-desc {
    padding: '2rem';
    margin-right: '3rem';
    /* font-size:'12px';
    color:'#707070' */
  }
  .footer-desc{
    padding:1rem;
  
  }
  .obj-body p {
    color: #444444;
    font-size: 15px;
    padding-right: 1rem;
  }
  .obj-body h3{
   margin-bottom: 0;
    color: #EF7622;
    font-size: 15px;
    font-weight: 600;
  }
  .obj-img {
    width: 105px;
    min-width: 105px;
    min-height: 85px;
    display: flex;
    /* margin-right: 1rem; */
    align-items: center;
  }
  .obj-body b{
    color: #444444;
  }
  .obj-img img {
    max-width: 100%;
  }
  
  .marquee {
    display: none !important;
  }
  .footerShell {
    width: 100vw;
    position: absolute;
    left: 0;
    padding-bottom: 90px;
  }
  .footerDiv {
    max-width: 95vw;
  }
  .pageDiv {
    max-width: 100vw;
  }
  .speaker {
    display: flex;
    flex-direction: column;
    justify-content: center;
    align-items: center;
  }
  
  @media screen and (max-width: 1399px) {
    .ipub-video {
      padding: 0 3.25rem;
    }
    .ipub-title {
      font-size: 28px;
      padding: 1.75rem 1.25rem 1.75rem 0;
    }
  }
  @media screen and (max-width: 1199px) {
    .ipub-video {
      padding: 0 3rem;
    }
    .ipub-title {
      font-size: 24px;
      padding: 1rem 1.25rem 1rem 0;
    }
    .logo-container {
        width: 50%;
    }
    .onc-logo img {
      max-height: 70px;
      margin: 0 0.5rem;
    }
    .ipub-logo img {
      max-height: 45px;
    }
    .ipub-prescription-info {
      height: 55px;
    }
    .ipub-prescription-info .current-title {
      font-size: 1rem;
    }
    .chapter span:last-child {
      font-size: 1rem;
      height: 54px;
      pointer-events: none;
    }
  }
  @media (min-width:969px) and (max-width:1163px){
    .obj-card{
      max-width: 100%;
    }
  }
  @media screen and (max-width: 1020px) {
    .ipub-wrapper {
      background-size: cover;
    }
    .mlr div {
      padding-bottom: 150px;
    }
    .isi-container {
      margin-left: 0.5rem;
    }
    .ISI-header p:first-child {
      font-size: 15px;
      font-weight: 700;
    }
    .ISI-header {
      padding: 16px !important;
    }
    .obj-card {
      min-height: 285px;
    }
  }
  @media screen and (max-width: 968px) {
    .mlr div:nth-of-type(even){
      padding:0px 2rem 0 2rem;
      
    }
    .ipub-navbar-container{
      justify-content: center;
    }
    .obj-body p{
      margin-bottom: 1rem;
    }
  
    .ipub-speaker p:first-child {
      text-align: center;
    }
    .top-ad-container {
      position: static !important;
      top: 0;
    }
    .ipub-video {
      padding: 0 3.25rem;
    }
    .ipub-title {
      font-size: 28px;
      padding: 1rem 1.25rem 1.75rem 0;
    }
    .ipub-top-indication {
      height: 0;
    }
    .logo-container {
      width: 100%;
      margin-top: 1rem;
      justify-content: center;
      align-items: center;
      padding: 0.25rem 0 0.5rem;
    }
    .ipub-title h1,
    .ipub-title h3{
      text-align: center;
      font-size: 28px;
    }
    .ipub-logo img {
      max-height: 55px;
      transform: translateX(-10px);
    }
    .onc-logo img {
      max-height: 75px;
      margin-left: 0;
    }
    .speaker-container {
      flex-wrap: wrap;
      justify-content: center;
      align-items: center;
      flex-direction: column;
    }
    .speaker-individual-container {
      width: 100%;
    }
    .obj-card {
      max-width: 100%;
      flex-direction: column;
      min-height: 120px;
      margin: 1rem 0;
    }
    .objectives{
      margin:0;
    }
    .obj-img{
      min-width: 70px;
      max-width: 70px;
      margin-bottom: 0;
    }
    .cred {
      padding-left: 0;
    }
    .ipub-speaker {
      max-width: 92vw;
    }
    .ISIBox {
      max-width: 90vw;
    }
    .AD300x250,
    .AD320x50L {
      display: none;
    }
    .ipub-title {
      width: 100%;
      font-size: 1.2rem;
      display: inline-block;
    }
    .ipub-logo {
      display: inline-block;
    }
    .ipub-header {
      flex-wrap: wrap-reverse;
    }
    .chapter-tab {
      width: 100%;
      font-size: 1rem;
      padding: 0.5rem;
    }
    .ipub-player {
      width: 90vw;
      padding-bottom: 0;
      margin-bottom: 2rem;
    }
    .active {
      font-size: 0.8rem;
      min-width: 7px;
      position: relative;
    }
    .active span {
      font-size: 0.7rem;
      color: white !important;
    }
    .ipub-chapters {
      flex-wrap: wrap;
    }
    .chapter {
      width: calc(6 / 100%);
      padding-left: 0.25rem;
      padding-right: 0.25rem;
      /* overflow: hidden; */
    }
    .mlr {
      max-width: 90vw;
      flex-direction: column;
      justify-content: center;
      align-items: center;
    }
    .mlr div {
      padding-bottom: 10px;
    }
    .ipub-speaker > h1 {
      padding-left: 0;
      text-align: center;
      font-size: 24px;
    }
    .intro {
      width: 55px !important;
      font-size: 0.5rem;
      padding-left: 0.25rem;
      padding-right: 0.25rem;
    }
    .intro.active {
      font-size: 0.8rem;
      width: 160px !important;
      padding-left: 0.5rem;
    }
    .ipub-wrapper {
      overflow-x: hidden;
    }
    .isi-container {
      width: unset;
    }
    .isiBox {
      max-width: 95vw;
    }
    .video-container {
      flex-direction: column;
      justify-content: center;
      align-items: center;
    }
    .ipub-video {
      width: 100%;
      max-width: 100vw;
    }
  }
  
  @media screen and (max-width: 1000px) and (min-width: 768px) {
    .shell {
      max-width: 100vw;
      overflow-x: hidden;
    }

  }
  #flyBanner {
    top: -195px !important;
  }
  @media screen and (max-width: 768px) {
    .speaker-individual-container {
      margin: 0 !important;
      padding: 1rem;
    }
    .obj-body {
      width: 100%;
      height: 100%;
    }
  }
  @media screen and (max-width: 548px) {
    .ipub-title h1 {
      font-size: 24px;
      padding: 0.5rem 0;
      margin-bottom: 0;
    }
    .ipub-title {
      padding: 0.75rem 0 0;
    }
    .ipub-prescription-info {
      min-height: 70px;
    }
    .ipub-prescription-info .current-title {
      line-height: 1.2;
      text-align: center;
    }
    .chapter span:last-child {
    line-height: 1;
  }
    .ipub-inner-wrapper {
      max-width: 99vw;
      margin-top: 3rem;
    }
    .ipub-player {
      width: 95vw;
    }
    .ipub-header {
      padding: 0 0.25rem;
      margin-top: .5rem;
    }
    .logo-container{
      margin-top: 0;
      padding: .25rem;
    }
    .ipub-speaker div p:first-child {
      font-size: 20px;
    }
    .chapter:last-child {
      border-right: none;
    }
  
    .active span:first-child {
      font-size: 1.3rem;
    }
    .chapter-tab {
      font-size: 1rem;
    }
    .ISIBox {
      max-width: 95vw;
    }
    .isi-container {
      margin-left: 0;
    }
    .ipub-video {
      padding: 0 1rem;
    }
  
    .onc-logo img {
      max-height: 68px;
      margin-left: 0;
      margin-right: 2rem;
    }
    .ipub-logo img {
      max-height: 40px;
    }
    .mlr {
      flex-wrap: wrap;
      padding-bottom: 1rem;
    }
    .mlr div {
      margin-right: 0;
      padding-bottom: 0;
      margin-bottom: 1rem;
      width: 100%;
    }
    .mlr p{
      font-size: 9px;
    }
    .mlr div img {
      max-width: 100% !important;
      padding: 0 2rem;
    }
    .speaker-container {
      position: relative;
    }
    .speaker-individual-container {
      flex-direction: column !important;
      flex-wrap: wrap !important;
      justify-content: center;
      margin: 0 !important;
    }

    .speaker-individual-container div p {
      font-size: 13px !important;
      text-align: center;
    }
    .speaker-container img {
      width: 172px;
      height: 172px;
    }
    .chapter-title {
      text-align: center !important;
    }
    .program-objectives h2 {
      font-size: 22px !important;
      line-height: 1.2 !important;
    }
  }
  
  @media screen and (max-width: 450px){
    .onc-logo img {
      max-height: 54px;
  
    }
  }
  
  /* brightcove video detail */
  
  .brightcove .video-js {
    float: none;
    width: 100%;
    height: 0;
    margin-bottom: 0;
    /* padding-bottom: calc((9 / 16) * 100%); */
  }
  .brightcove .video-js {
    float: none;
    width: 100%;
    height: 600px;
    padding-bottom: calc((9 / 16) * 100%);
  }
  @media screen and (max-width: 768px) {
    .brightcove .video-js {
      height: 400px;
    }
  }
  @media screen and (max-width: 540px) {
    .brightcove .video-js {
      height: 300px;
    }
  }